What are Ayr Cannabis Dispensary Port St. Lucie's hours?

Ayr Cannabis Dispensary Port St. Lucie is typically open 9am–8:30pm daily. Hours may shift on holidays — check the hours panel above for the most current schedule.

Where is Ayr Cannabis Dispensary Port St. Lucie located?

Ayr Cannabis Dispensary Port St. Lucie is located in Port St. Lucie, Florida. Use the map and 'Get directions' button above for turn-by-turn navigation, plus on-site parking and ADA-accessible entry.

Can I order online for pickup?

Yes — tap 'Shop Menu' to browse the live menu and place a pickup order. Most orders are ready within 15–30 minutes; we'll text you when yours is set.

Do you offer delivery?

Delivery isn't available from this location, but you can place a pickup order online and we'll have it ready when you arrive.

What should I bring with me?

Bring your valid state-issued medical marijuana card and a government-issued photo ID.

What payment methods do you accept?

We accept cash and most debit cards (with a small ATM fee). Credit cards are not accepted at the register due to federal banking restrictions; an on-site ATM is available.

Ayr Cannabis Dispensary Port St. Lucie

Name: Ayr Cannabis Dispensary Port St. Lucie
Address: 10941 US Highway 1, Port St. Lucie, FL, 34952, US
Telephone: (772) 249-4199
Rating: 4.6

4.6· 883 reviews(772) 249-4199

10941 US Highway 1, Port St. Lucie, FL 34952

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About Ayr Cannabis Dispensary Port St. Lucie

Ayr Cannabis Dispensary Port St. Lucie is a cannabis dispensary in Port St. Lucie, Florida, right on US Highway 1. We serve patients across Port St. Lucie, Jensen Beach, Fort Pierce, and the wider Treasure Coast area. Our budtenders take time to help you find what works, with no pressure either way. You can browse flower, vapes, edibles, concentrates, tinctures, and topicals, and the full menu is online for pickup. A Florida medical marijuana card is required to shop here, and you must be 18 or older.

Ayr Cannabis Dispensary Port St. Lucie storefront — Port St. Lucie, FL

Hours, contact & directions

Closed · Opens 9am

Monday9am–8:30pm
Tuesday9am–8:30pm
Wednesday9am–8:30pm
Thursday9am–8:30pm
FridayToday9am–8:30pm
Saturday9am–8:30pm
Sunday10am–8pm

Holiday hours may differ. Check the home page banner before stopping by.

10941 US Highway 1, Port St. Lucie, FL 34952
(772) 249-4199

Port St. Lucie, FL

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What guests say about Ayr Cannabis Dispensary Port St. Lucie

Real reviews from real visitors. We're proud of every five-star moment.

4.6

Based on 883 guest reviews

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“Love the staff they are my favorite 😍”

Stefanie Abrantes

4 mo ago

“Ports st Lucie is the best hands down!!!!”

Sean Scott

Today

“Katie was absolutely wonderful, helped me figure out what I needed and wanted and was extremely helpful the whole time. Was a great experience and will be coming again!”