What are Ayr Cannabis Dispensary Lake City's hours?

Ayr Cannabis Dispensary Lake City is typically open 9am–8:30pm daily. Hours may shift on holidays — check the hours panel above for the most current schedule.

Where is Ayr Cannabis Dispensary Lake City located?

Ayr Cannabis Dispensary Lake City is located in Lake City, Florida. Use the map and 'Get directions' button above for turn-by-turn navigation, plus on-site parking and ADA-accessible entry.

Can I order online for pickup?

Yes — tap 'Shop Menu' to browse the live menu and place a pickup order. Most orders are ready within 15–30 minutes; we'll text you when yours is set.

Do you offer delivery?

Delivery isn't available from this location, but you can place a pickup order online and we'll have it ready when you arrive.

What should I bring with me?

Bring your valid state-issued medical marijuana card and a government-issued photo ID.

What payment methods do you accept?

We accept cash and most debit cards (with a small ATM fee). Credit cards are not accepted at the register due to federal banking restrictions; an on-site ATM is available.

Ayr Cannabis Dispensary Lake City

Name: Ayr Cannabis Dispensary Lake City
Address: 1720 W US Hwy 90, Lake City, FL, 32055-4718, US
Telephone: (386) 400-3935
Rating: 4.9

4.9· 1137 reviews(386) 400-3935

1720 W US Hwy 90, Lake City, FL 32055-4718

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About Ayr Cannabis Dispensary Lake City

Ayr Cannabis Dispensary Lake City is a cannabis dispensary in Lake City, Florida, just off West US Highway 90 near I-75. We serve patients across Lake City and the wider North Florida area. Our budtenders take time to help you find what works, with no pressure either way. You can browse flower, vapes, edibles, concentrates, tinctures, and topicals, and the full menu is online for pickup. A Florida medical marijuana card is required to shop here, and you must be 18 or older.

Ayr Cannabis Dispensary Lake City storefront — Lake City, FL

Hours, contact & directions

Closed · Opens 9am

Monday9am–8:30pm
Tuesday9am–8:30pm
Wednesday9am–8:30pm
Thursday9am–8:30pm
FridayToday9am–8:30pm
Saturday9am–8:30pm
Sunday10am–8pm

Holiday hours may differ. Check the home page banner before stopping by.

1720 W US Hwy 90, Lake City, FL 32055-4718
(386) 400-3935

Lake City, FL

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What guests say about Ayr Cannabis Dispensary Lake City

Real reviews from real visitors. We're proud of every five-star moment.

4.9

Based on 1137 guest reviews

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“Outstanding I couldn’t ask for anything better thank you it was awesome 👏🏾”

Angela

Today

“AYR is my favorite of the dispensaries. The price are good the bud tenders are knowledgeable about the products they sell. Garry has to be one of my top two favorite tenders.”